The IAKP are a group of practitioners and other interested parties who seek to support and encourage the safe, responsible and legal use of Kambo through training, awareness raising, knowledge development and sharing, research, professional behavior and best practice.

Recently, we have found that the skin secretions of the Amazonian tree frog Phyllomedusa bicolor contains molecules with antitumor and angiostatic activities and identified one of them as the antimicrobial peptide dermaseptin (Drs) B2.

Screening for new bioactive peptides in South American anurans has been pioneered in frogs of the genus Phyllomedusa. From Vittorio Erspamer findings, this genus has been reported as a "treasure store" of bioactive peptides.

A frog used for "hunting magic" by several groups of Panoan-speaking Indians in the borderline between Brazil and Peru is identified as Phyllomedusa bicolor. This frog's skin secretion, which the Indians introduce into the body through fresh burns, is rich in peptides

Three naturally occurring dermorphin-like peptides from the skin of the frog Phyllomedusa bicolor, and some substituted analogs were synthesized, their binding profiles to opioid receptors were determined, and their biological activities were studied in animals.

Deltorphins are endogenous linear heptapeptides, isolated from skin extracts of frogs belonging to the genus Phyllomedusa, that have a higher affinity and selectivity for delta opioid binding sites than any other natural compound known.